منابع مشابه
Drosophila melanogaster: a genome sequenced.
The release of the full genome sequence of Drosophila melanogaster in March of 2000 must be heralded both as a milestone in Drosophila biology and genetics and as a triumph of modern biotechnology. But the true value of this accomplishment can be found in its beginnings, during a plenary session at a 1978 Drosophila meeting in La Jolla, California. The first speaker of the session was peppered ...
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Genomes of the month This month, four genomes from two different species will be discussed. The first organism, Rhodopseudomonas palustris, is a metabolic ‘fox’, in that it can do many different things. R. palustris is one of the most metabolically versatile bacteria known – it can grow utilizing any one of the four modes of metabolism that support life. In contrast, the three different Prochlo...
متن کاملmiReader: Discovering Novel miRNAs in Species without Sequenced Genome
Along with computational approaches, NGS led technologies have caused a major impact upon the discoveries made in the area of miRNA biology, including novel miRNAs identification. However, to this date all microRNA discovery tools compulsorily depend upon the availability of reference or genomic sequences. Here, for the first time a novel approach, miReader, has been introduced which could disc...
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In The Strongest Boy’s title essay, Reilly tells the story of a German newborn whose strangely muscled physique is due to a frame shift mutation in the aforementioned muscle inhibitor, myostatin. As a result, his 7-month-old thighs look like those of a miniscule Lance Armstrong. His mother, a heterozygote and professional athlete, already has hidden him from public view, shielding him from scru...
متن کاملThe Characterization of Twenty Sequenced Human Genomes
We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals with severe hemophilia A and ten "control" genomes. We summarize the number of genetic variants emerging from a study of this magnitude, and provide a proof of concept for ...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2000
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac0029049